兔抗cd86多---抗體

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ground:

this gene encodes a type i membrane protein that is a member of the immunoglobulin superfamily. this protein is expressed by antigen-presenting cells,&it is the ligand for two proteins at the cell surface of t cells, cd28 antigen&cytotoxic t-lymphocyte-asso-ted protein 4. binding of this protein with cd28 antigen is a costimulatory signal for activation of the t-cell. binding of this protein with cytotoxic t-lymphocyte-asso-ted protein 4 negatively regulates t-cell activation&diminishes the immune response. alternative splicing results in several tran variants encoding different isoforms.

applications:

elisa, ihc

name of antibody:

cd86

immunogen:

fusion protein of human cd86

full name:

cd86 molecule

synonyms:

b70; b7-2; b7.2; lab72; cd28lg2

swissprot:

p42081

elisa recommended dilution:

5000-10000

ihc positive control:

human gastric cancer

ihc recommend dilution:

40-200